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1-[(4-氯苯基)甲基]-2-(1-吡咯烷甲基)-1H-苯并咪唑;
简介
吡咯咪唑又叫1-[(4-氯苯基)甲基]-2-(吡咯烷-1-基甲基)苯并咪唑，克立咪唑。具有抗组胺作用，具有中等度的镇静作用及明显的止痒作用。最新研究表明其具有抗丙型肝炎病毒的作用。本品能延长心房肌有效不应期，有治疗房扑的报道。副作用少见。
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瑞格列净乙酸酯
简介
瑞格列净乙酸酯是瑞格列净的一种口服前药，瑞格列净是一种苄基吡唑葡糖苷类的肾钠-葡萄糖共转运体亚型2（SGLT2）抑制剂，具有降血糖活性。给药和吸收后，非活性前药转化为其活性形式remogliflozin，并选择性作用于钠-葡萄糖共转运体亚型2（SGLT2）。
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他波宁; 水甘草碱; 它勃宁; 柳叶水甘草碱; 它勃宁盐酸盐; 盐酸它勃宁
简介
本品为植物提取物，用作医药原料，具有降压的作用。用于含量测定/鉴定/药理实验等。
别名
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八氢-2H-1-苯并吡喃-2-酮; 双环壬内酯; 八氢-2H-吡喃-2-酮; 八氢-2H-苯并吡喃-2-酮
简介
本品为为允许使用的食用香料，可做食品添加剂。
CAS:444805-28-1
分子式:C27H52N3O7P
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Brincidofovir
简介
Brincidofovir is an alkoxyalkyl ester prodrug containing the synthetic, acyclic nucleoside monophosphate analog cidofovir linked, through its phosphonate group, to a lipid, 3-hexadecyloxy-1-propanol, with antiviral activity against double-stranded DNA viruses. Upon oral administration, brincidofovir crosses the intestinal wall and penetrates target viral-infected cells before being cleaved to the free antiviral agent cidofovir. In turn, cidofovir is phosphorylated by pyruvate kinases to its active metabolite cidofovir diphosphate. Cidofovir diphosphate, bearing structural similarity to nucleotides, competes with deoxycytosine-5-triphosphate (dCTP) for viral DNA polymerase and gets incorporated into the growing viral DNA strands. As a result, it prevents further DNA polymerization and disrupts DNA replication of viruses. Compared to cidofovir, which is given intravenously, hexadecyloxypropyl-cidofovir shows better oral bioavailability, less toxicity and enhanced cellular penetration.
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